Argireline: the best cosmetic component of 2018


If desired, Argireline is a little known cosmetic component. However it has a wonderful effect if we are looking for facial rejuvenation. And it is that Argireline has begun to stand out for its "botox effect", in the treatment for wrinkles and expression lines. But is it true that a cosmetic can have "Botox effect"? And its effect is as effective and durable as that obtained with "Botox" (Botulinum Toxin type A) in medical consultations?

In this article, we will talk about Argireline and try to answer these questions. But first...

What is Argireline?

Argireline is a hexapeptide developed by molecular engineering that has revolutionized the world of current cosmetics. Since it has been specifically designed to fight wrinkles and expression lines, presenting a significant and proven effectiveness against wrinkle formation.

Current biochemical knowledge of the basic mechanisms of anti-wrinkle action has allowed the synthesis of this peptide that is considered a topical alternative to Botulinum Toxin A - or Botox -, although its effect is not as potent and its mechanism of action is different.

How does Argireline work?

To understand how Argireline works, it is necessary to know that the muscles contract when they receive neurotransmitters (such as acetylcholine) released by vesicles to the neuronal synapse (union between neurons), and this contraction of the facial muscles continuously favors the appearance of wrinkles expression. So the relaxation of these muscles will prevent wrinkles from forming.

In the neuronal synapse there is a protein complex called SNARE (formed by proteins such as VAMP, syntaxin and SNAP-25) that is essential for the release of the necessary acetylcholine for muscle contraction to occur.

Well, the Argireline hexapeptide is analogous to the N-terminal end of SNAP-25, and therefore competes with the natural protein for a position in the SNARE complex. When this complex is slightly destabilized by the binding of Argireline instead of the natural protein, the vesicles cannot anchor and release acetylcholine efficiently, so that muscle contraction is attenuated, and the muscle relaxes, thus preventing wrinkle formation and attenuating existing ones.

This is how Argireline works by reducing the depth of wrinkles caused by the contraction of the expression muscles. But it is a much milder alternative to Botulinum Toxin type A, since although it acts topically on the same wrinkle formation mechanisms, it does so very differently. Since Botulinum Toxin type A paralyzes the muscle by selectively blocking the release of acetylcholine in the neuromuscular junction, it fragments the SNAP-25 protein irreversibly preventing the formation of the SNARE complex and thus preventing the nerve signal from being transmitted, so that the muscle cannot contract and is paralyzed.

Simply put, we can say that Argireline works by relaxing and attenuating the muscle contraction that causes wrinkles in our skin.

The properties of Argireline

The main property of the component is to prevent the appearance of wrinkles and expression lines, thanks to its tensor effect on the skin. It not only prevents but improves the appearance of existing wrinkles. Having its main effect on the eye contour, as well as forehead wrinkles. It also has the advantages:

  • Of not having risks because its application is topical - unlike Botox.
  • Do not be toxic.
  • And be hypoallergenic.

Contraindications? Does not have. Only that the effects on the skin are weaker than those generated by Botox and that it is true, you should apply it permanently, because otherwise its effect ends.

Argireline is a great cosmetic component, in fact it is one of the components of our SmartBright by Dr. Parpados that together with Trylagen makes it one of our most valued and sought after products. Have you tried it yet?